As you might expect, the
polio vaccine is a medicine that is given to prevent
polio (also called poliomyelitis).
There are two general types of polio vaccine. One type is an inactivated vaccine (the
IPV), meaning that the vaccine contains no live
poliovirus. The other type is an oral vaccine, which contains live but weakened poliovirus.
History of Polio and the Polio Vaccine
A 1916 polio epidemic in the United States killed 6,000 people and paralyzed 27,000 more. In the early 1950s, there were more than 20,000 cases of polio each year. Vaccination began in 1955. By 1960, the number of
polio disease cases had dropped to about 3,000. The last cases of paralytic poliomyelitis caused by endemic
polio transmission of wild virus in the United States were in 1979, when an outbreak occurred among the Amish in several Midwestern states. The success of the polio vaccine in the United States and other countries sparked a worldwide effort to eliminate polio.
The inactivated polio vaccine was licensed in 1955 and was used extensively from that time until the early 1960s. In 1961, the oral vaccine was licensed. This was the vaccine of choice in the United States and most other countries after its introduction. However, the oral vaccine can cause a rare but serious reaction called vaccine-associated paralytic poliomyelitis. When an enhanced-potency inactivated polio vaccine became available in 1998, it was recommended that the oral vaccine no longer be used. In 2000, the use of the oral vaccine in the Unites States was discontinued.